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The first trimester of pregnancy: why is it important to get a medical check up?

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What kind of medical tests do you have to undergo during the first trimester of pregnancy, regardless of the first ultrasound of the 12 weeks? We detail all the controls that you must pass. Everything you need to know!

At the beginning of pregnancy, during the first trimester of pregnancy, if possible, before 13 weeks and, in any case, at the first gynecological examination, the expected examinations are: complete analysis, blood group and Rh factor, Rubella virus, toxoplasmosis antibodies (if the mother is not immune, this analysis should be repeated once every trimester), HIV 1-2 (AIDS), syphilis, hepatitis B and C. If the woman belongs to n Rh-negative blood group, the Coombs test (to be repeated every trimester) will also be performed. Also, during the first trimester of pregnancy, other controls are planned, which we detail below.

Controls of the first trimester of pregnancy

Transaminases (GOP and GPT)

  • Assessing the concentration of these enzymes in the blood, indications can be obtained from the liver function.

Creatinine and urea

  • Increased creatinine may indicate a malfunction of the kidneys, although it is not often seen for the first time during pregnancy. Also, if urea values are altered, they may indicate the presence of dehydration or kidney disease.

Cholesterol and triglycerides

  • Cholesterol and triglyceride levels increase significantly during pregnancy, so they are monitored in a special way each quarter, starting in the first trimester of pregnancy.

Thyroid hormones (T3, T4, and TH)

  • This test is performed to prevent congenital hypothyroidism, a condition caused by lack of iodine during pregnancy.

Uric acid

  • It is performed to detect a disorder in the metabolism. If the uric acid level is high, a special diet is prescribed for the mother.


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  • This test measures the amount of sugar in your blood. Although the values are normal, it should be performed a minimum of 2-3 times in the course of pregnancy. A value that is persistently higher than the limit justifies a serious suspicion of the presence of diabetes and therefore requires a more specific control.

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Biochemical screening (prenatal screening)

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  • It consists of analyzing the fetal enzymes (BHGC, estriol, and alpha-fetoprotein) present in the maternal blood, in order to evaluate the risk of the fetus suffering from any chromosomal abnormality. However, the results of these analyses that occur in the first trimester of pregnancy are not determinative but should be evaluated together with the results of ultrasound at week 12, where the gynecologist measures the nuchal fold of the fetus, among others data. If the risk is 1 in 250 or greater, amniocentesis is recommended.

Finally, during this first trimester of pregnancy, urinalysis, the corresponding ultrasound, weight and blood pressure monitoring should be performed.

Also Read: Did you know that stress can affect your fertility?

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